Future of Global Antibody Drug Conjugates Market 2016 – 2024

New York, NY — (SBWIRE) — 01/19/2017 — Antibody drug conjugates are composed of three parts- an antibody specific to the target associated antigen, antigen that has restricted expression on normal cell, a cytotoxic agent designed to kill target cancer cells and a chemical linker to attach cytotoxic agent to the antibody. Antibody drug conjugates have therapeutic potential and contains both technological and developmental challenges. Antibody drug conjugates are considered to be the new age of therapeutic agent. They combine the targeting ability of monoclonal antibody and the target specific cell killing ability of cytotoxic drugs. The success of this technology has become possible only with the increasing technological advancements. Antibody drug conjugates is the new class of therapeutic agent that is gaining attention from both large and small pharmaceutical companies. The potency of the cytotoxic drug in antibody drug conjugate is 100-1000 fold more than the potency of cytotoxic drug when it acts alone. Though this technology provides presence to maximum large pharmaceuticals companies, the capabilities for the development of ADC still lies with very few companies. There are many products under pipeline. Most development today has been carried out under license agreements. There are only three antibody drug conjugates that have received approval from the U.S. Food and Drug Administration (FDA). The first drug Mylotarg among them was withdrawn from the market by its manufacturers in June 2010. It was used to treat acute myelogenous leukemia but a clinical trial showed that the drug has only increased the mortality rate among the acute myelogenous leukemia patient and had no benefit over the conventional therapy. Therefore the antibody drug conjugate market is segmented to only two approved products.

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The global market for antibody drug conjugates is expected to be driven by the advancement in medical technology. The key drivers of the market are the increasing cases prevalence of cancer, growing ageing population and increase in obese population. Moreover, the increasing research activities on antibody therapies, preclinical research, more research on advanced drug discoveries and increasing research on oncology diseases and the growing collaboration between research institutes, Biotechnology and Biopharmaceuticals companies is also acting as a fuel to the market and is expected to drive the market of antibody drug conjugates within the forecast period of 2016-2024. However, the high cost of the procedures and the lack of fund can be the restraint for the growth of this market.

The number of companies developing methods for antibody drug conjugates technology has not significantly changed in recent years. The increasing investment by the pharmaceutical and Biotechnology companies is expected to drive the market. Based on the product type the market is segmented to Adcertis and Kadcyla. Adcetris (brentuximab vedotin) is drug indicated for patients suffering with classical Hodgkin lymphoma (HL) after failure from at least two multi-agent chemotherapy regimen in patient who are not auto-HSCT candidates or patient with failure of autologous hematopoietic stem cell transplantation, HL patients at high risk of relapse or progression as post- auto- HSCT consolidation and lymphoma patient after failure of at least one prior multi-agent chemotherapy. Drugs was granted accelerated approval for Biologics License Application (BLA) by the U.S FDA for its usage in relapsed and refractory Hodgkin’s lymphoma and large cell lymphoma. Kadcyla (Trastuzumab emtansine) it is the first HER2-targeted treatment of its own kind for metastatic breast cancer. It contains two cancer- fighting drugs in one. It contains monoclonal antibody trastuzumab (the same monoclonal antibody in Herceptin) and chemotherapy drug. Kadcyla is treatment that targets HER2.

By end user, the global antibody drug conjugates market has been segmented into Hospitals, Specialized Cancer Centers, Academic Research Institutes, Biotechnology Companies, Biopharmaceutical Companies and others. Antibody drug conjugates are used in cancer cell therapy and for research and clinical trials.

By regional presence, antibody drug conjugates market is segmented into five key regions viz. North America, Latin America, Europe, Asia-Pacific, and the Middle East & Africa. North America will continue to dominate the antibody drug conjugates market as it has high experienced professionals and better healthcare facilities. Europe is expected to hold second largest market share in global antibody drug conjugates market. The growing government initiatives and increasing number of Biotechnology and Biopharmaceutical companies in APAC is also driving the market of antibody drug conjugates in APAC.

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Some of the major players in global antibody drug conjugates market include Genentech USA, Inc., Seattle Genetics, F. Hoffmann-La Roche Ltd and Takeda Pharmaceuticals.

All Protesters Receive a Special Free Gift for Unity from Project NatureConnect

Whole Body, Mind and Life

Powerful Scientific Unification Path is Validated and Offered: Politicians, Educators and Students Alerted as Grand Jury Examines Human Rights Violations.

The life of our planet is also our life and as we disturb it we disturb ourselves. We suffer a wide range of troubles by not thinking and relating with all 54 of our natural senses ”

— Michael J. Cohen, Ed.D., Ph.D. directs Project NatureConnect.

FRIDAY HARBOR, WASHINGTON, USA, January 19, 2017 /EINPresswire.com/ — Dear Editor

In 1948 I occasionally marched, gave speeches and sang songs as part of protests that supported causes of the United World Federalists and Progressives. I did this because their platforms called for called for personal and global unity then as they do now. For sixty-eight years, as well as centuries before, these actions for peace, justice and the environment have only made slow headway. This is because a powerful, unifying component has always been missing from them.

It is outrageous that in 2016 a candidate for U. S. President bragged to the nation that he could unify us while also stating that he could kill an innocent person in full public view and still win the election. Incredibly, that candidate won. How unifying is that?

How could this paradox happen? What unifying component are our protests, sciences and education still missing? Our disunity will continue to worsen as long as the organic art and science of Albert Einstein’s unified field “GreenWave-54” is omitted from our actions and personal relationships. There is no excuse for this. GreenWave-54 is available as per the release, below. Why not be part of the solution? Publish its message in some form and prevent the life of Earth and us from continuing to fall apart. Help folks apply the unifying “GreenWave glue” we desperately need. Let them know that it is available, free, online or as a softcover book from Amazon.com. The new book “With Justice for All” demonstrates that it is impossible to responsibly unify to the benefit of all without using GreenWave-54.

Is there anyone on your staff interested in reversing our personal, social and environmental dilemmas instead of continuing to just report that we have them? Can you share this release with that staff member(s) so they can contribute to personal and global well-being?

For Peace on Earth Through Peace With Earth,

Michael J. Cohen, Ed.D, Ph.D.

For Immediate Release:
Also available at www.ecopsych.com/wjfareview

All Protesters Receive a Free Gift for Unity: Scientific Unification Path is Validated

San Juan Island, WA. Jan 18, 2017: A new book, “With Justice for All: The Investigation of a 54-Sense Organic Technology of Behavior,” gives readers and a grand jury the missing glue” that we need to interlock ourselves in unity with each other and the world. The paperback or e-book contains the testimony of 29 witnesses in a metaphor class action suit about the violation of our constitutional rights to life and information by the U.S. Department of Education. This violation prevents the unification that we need today.

The defendants are accused of negligence because they withhold from the public “GreenWave-54” a social technology that brings 46 biological senses into play that we are presently educated to suppress. It enables us to connect all these senses to natural areas which strengthens their unifying powers. This enables us to reduce by 85 percent the lies, greed and madness that increasingly pull the world apart today.

In comparison to 1974, Earth is now 45 percent in natural-resource deficit each year and counting. Half the species alive in 1972 have been eradicated while mental illness has increased by half and this trend is true for most other disorders, too. Nobody knows the source of this catastrophe or has a cure for it because unifying GreenWave-54 information has been concealed by the defendants.

The author of “With Justice for All”, Dr. Michael J. Cohen, Director of Project NatureConnect has written ten previous books on sensory organics. He says “This probe demonstrates to it jury and the reader that the life of our planet is also our life and as we disturb it we disturb ourselves. We suffer a wide range of troubles by not thinking and relating with all 54 of our natural senses, including the fact that we have 54 of them. Without them we weaken the life and integrity of our planet and ourselves by 85 percent. This reduces our sensibility and resilience to what ails us personally, socially and environmentally.”

“’With Justice for All’ is a 78 page, illustrated. softcover book from Amazon.com”, said Cohen. “However, because it makes a critical contribution, it’s text is also free, online, and as an e-book from www.Project NatureConnect.net. There it includes links to how to learn, apply and teach the warrantied GreenWave-54 process independently or as part of online CEU courses and funded degree programs. To the benefit of all of life, when GreenWave-54 is added to our relationships or livelihood it unifies and supports them while it reduces budgets.”

Contact: Mike Cohen 360-378-6313 nature@interisland.net www.ecopsych.com/mjcohen.html

Visit: www.ProjectNatureConnect.net It includes free links to the book along with its methods and materials.

Michael J. Cohen
Project Nature Connect
360 378 6313
email us here

Was General George Armstrong Custer Assassinated?

Assassinating Custer is Book One of The Disclosure Files. Based on the never before published Manuscript of William D. Nugent who fought and survived the Battle of Little Bighorn. Guy Lozier has released his 4th novel. Presenting new history changing information about the Battle of Little Bighorn, acclaimed author Guy Lozier delves into questions arising from William’s manuscript.
BILLINGS, Mont.Jan. 19, 2017PRLog — Author/Director/Producer Guy Lozier, after nearly a year of research, has finally published the novel Assassinating Custer.


“I was approached by an actor from one of my movies who asked me to take a look at a manuscript. It blew my mind. This information was history changing. After digging through information for nearly a year, I found more than I could have bargained for,” Guy replied when asked why he chose to write this novel.

Did President Grant’s Administration funnel repeating rifles to the Indians to set up a False Flag Event?

​Did General Sheridan order General Terry to stop preventing miners from sneaking onto Indian Lands to mine gold?

Did General Crook purposely attack peaceful Cheyenne Indians to stir them up?

Were there meetings in the White House to plan a Secret War?

Was President Grant’s Administration considered the most corrupt one of the 19th century?

Why did General Custer Arrest President Grant’s son?

Why did General Custer testify against President Grant’s brother?

Why did President Grant’s son call General Custer a liar in the press?

Did President Grant send geologists onto Indian Land illegally to search for gold?

Did members of President Grant’s Administration hide documents proving the Indians’ innocence of the lies told in the press by Grant’s Administration?

Why did Captain Benteen & Major Reno refuse to follow their orders given to them by General Custer concerning the Battle of Little Bighorn?

Why did General Terry, General Crook, Major Reno, and Captain Benteen lie about the Battle of Little Bighorn?

Why did General Terry withhold his forces from the Battle of Little Bighorn while Major Reno and Captain Benteen were fighting for their lives?

Was General Custer married to two women?

Did General Custer have two sons?

Did General Custer free an Indian woman from one of his scouts who was about to rape and kill her right before the Battle of Little Bighorn started?

All these questions and more are discussed in the novel…

Other Novels by Guy Lozier:

Book 1& 2 of The Mind Rift Saga

The Eternal: Guardian of Light

Scene from the novel – https://www.youtube.com/watch?v=G-7_7XICbMU

The Morantian

Book 1 of The Millennial Cycles

Menazia Reborn

Web Site:

The Disclosure Files: Assassinating Custer

Guy is considering movie production for this story.

Guy Lozier welcomes your comments…you can reach Guy at finalter@hotmail.com

Story by: Tim Biswell

Contact
Higher Destiny Productions
***@hotmail.com

Photos: (Click photo to enlarge)

Infinite Offspring Films Logo Assassinating Custer Image Provided by Randy Dunning Jr The Eternal: Guardian of Light The Morantian Menazia Reborn

Read Full Story – Was General George Armstrong Custer Assassinated? | More news from this source

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Separate U.S. Airstrikes Kill 2 Senior al-Qaida Leaders in Syria

WASHINGTON, Jan. 19, 2017 — Two senior al-Qaida operatives were killed recently in separate U.S. airstrikes in Syria, Pentagon Press Secretary Peter Cook said in two statements issued today.

Mohammad Habib Boussadoun al-Tunisi, an al-Qaida external operations leader, was killed by a U.S. precision airstrike Jan. 17 near Idlib, Syria, Cook said in a statement. The deceased terrorist, a Tunisian, was involved in extremist facilitation and external operations and has been connected to terrorist plots to attack Western targets.

The terrorist arrived in Syria in 2014 after spending several years in countries across Europe and the Middle East, where he maintained ties with multiple extremists, said Cook, adding the terrorist’s death will degrade al-Qaida’s pool of experienced, well-connected facilitators and fighters with external operations experience.

In a separate statement, Cook said U.S. forces killed Abd al-Jalil al-Muslimi, an al-Qaida facilitator, in a Jan. 12 precision airstrike near Saraqib, Syria.

Muslimi, a Tunisian, was trained by the Taliban in the late 1990s, when he facilitated extremist travel for the terror group, Cook said. He had extensive and long-standing ties to numerous al-Qaida external operations planners and terrorists. 

Cook said Muslimi’s death will degrade Al-Qaida in Syria’s access to that cadre of veteran plotters, which will likely disrupt its ongoing terror plotting.

Muslimi’s role will be difficult for al-Qaida to fill, Cook said, and the United States will continue to take action to deny these terrorists a safe haven in Syria from which to plot to attack the United States, its allies or its interests.

U.S. Airstrikes Kill 80 ISIL Fighters in Libya, Carter Says

WASHINGTON, Jan. 19, 2017 — The overnight U.S. precision airstrikes on two Islamic State of Iraq and the Levant training camps near Sirte, Libya, are estimated to have killed more than 80 enemy fighters, Defense Secretary Ash Carter said today.

On the eve of leaving his position as defense secretary, Carter told reporters at the Pentagon the airstrikes were vital in the American and coalition forces’ campaign to “deal ISIL the lasting defeat it deserves.”

The secretary said many of the estimated dead were fighters who had converged on the camps after fleeing from local partner forces that cleared Sirte last month with U.S. help. Sirte is nearly 28 miles southwest of the training camps that were struck last night.

Strikes Targeted External Plotters

The operation involved the United States in conjunction with its partners and Libya’s Government of National Accord, Pentagon Press Secretary Peter Cook said.

“The fighters training in these camps posed a security risk to Libya, its neighbors, our allies in Africa and Europe, and to the United States and its interests,” he said.

“Importantly, these strikes were directed against some of ISIL’s external plotters, who were actively planning operations against our allies in Europe,” Carter noted. “These were critically important strikes for our campaign and a clear example of our enduring commitment to destroy ISIL’s cancer — not only in Iraq and Syria, but everywhere it emerges.”

Strikes Help Sirte’s Liberation

As the U.S. assessment of the airstrikes in Libya continues, Cook said, the initial analysis is the strikes were successful in destroying the camps, and their destruction will degrade ISIL’s ability to threaten the Libyan people or disrupt efforts to stabilize Sirte after its liberation.

Two U.S. Air Force B-2 Spirit bombers, which took off from Whiteman Air Force Base, Missouri, primarily conducted the joint direct attack munitions hit both camps, the press secretary said.

“The use of the B-2 demonstrates the capability of the United States to deliver decisive precision force to the Air Force’s Global Strike Command over a great distance,” he noted, adding that the use of the bombers was a decision by commanders, given the capabilities of the platform and the requirements of the mission.

The spokesman showed surveillance video at one of the camps where he described ISIL members as moving equipment such as homemade bombs and shells.

“We have been watching [the training camps] for some time,” he added.

Counter-ISIL Progress in Iraq, Syria

The secretary said while the airstrikes in Libya were carried out, gains were made in Mosul, Iraq, by the Iraqi security forces.

 “Our local partners in Iraq, with our advice and assistance, managed to secure all critical areas in eastern Mosul, Carter said. “As they now prepare to clear the western part of Mosul, I’m confident that ISIL’s days in Mosul are numbered.”

Cook said work to clear pockets of resistance remains, but nearly all of Mosul east of the Tigris River is in Iraqi hands for the first time in two-and-a-half years.

“Iraqi security forces now control the eastern ends of all five bridges linking east and west Mosul. And Prime Minister [Haider] al-Abadi and Iraqi military commanders have hailed this as a major accomplishment,” he said.

Senior ISIL Leader Killed in Raqqa

And, while partner forces continue to isolate the city of Raqqa, Syria, Cook confirmed the death of Abu Anas al-Iraqi, a member of ISIL’s senior leadership council, following a raid on Jan. 8 as the terrorist traveled to Raqqa.

“Al-Iraqi was a long-time associate of ISIL’s senior leadership, dating back to its origins of Al-Qaida in Iraq. He oversaw media and financial operations and was a member of ISIL leader Abu Bakr al-Baghdadi’s inner circle,” Cook said.

Before 2007, al-Iraqi was chief propagandist for al-Qaida in Iraq and incited and directed attacks against U.S.’ and coalition forces in Iraq, the press secretary added.

“His death is a reminder to ISIL’s leadership that they will find no shelter anywhere on the battlefield. And as Secretary Carter just described, the coalition and our local partners have seized every opportunity to accelerate ISIL’s defeat. The events of the last 24 hours certainly demonstrate that,” Cook said.

(Follow Terri Moon Cronk on Twitter: @MoonCronkDoD)

U.S. EPA and Customs joint operations at Southern California ports result in fines and seizure of illegal engines and pesticides

News Releases from Region 09

01/19/2017

Contact Information: 

LOS ANGELES — Today, the U.S. Environmental Protection Agency and U.S. Customs and Border Protection announced $217,998 in fines and more than 5,325 items seized or denied entry to the United States. These are the latest results of continued joint operations at the ports of Los Angeles and Long Beach targeting foreign-made engines, including scooters, ATVs, chainsaws and construction equipment without proper emission controls, as well as pesticides that violate federal law.

“EPA and Customs have been working closely together to ensure imported engines meet air quality requirements,” said Alexis Strauss, EPA’s Acting Regional Administrator for the Pacific Southwest. “The enforcement cases announced today will prevent more than 1.5 million pounds of harmful air pollutants from being emitted into our air annually.”

Under the joint initiative, EPA has been conducting regular inspections with CBP at California ports of entry since 2014. With more than 40 percent of containerized goods coming into the U.S. through Los Angeles and Long Beach, the focus has been on engines, vehicles and pesticides. Mobile sources, such as on-road and off-road vehicles, are one the largest sources of air pollution in California and account for approximately 20% of PM2.5 (fine particulate matter up to 2.5 microns in diameter) and 83% of nitrogen oxide emissions.

Watch a new 4-minute video about EPA’s work at the ports, including a deeper look on how inspections, including laboratory testing, are conducted: https://youtu.be/QjNR2eDeTSw

Several companies were found to have imported vehicles and engines without certification or proper emissions controls. Engines operating without adequate controls emit excess carbon monoxide, hydrocarbons and nitrogen oxides, which can cause respiratory illnesses, aggravate asthma and lead to the formation of ground level ozone or smog. These inspections also targeted companies attempting to import unregistered or improperly labeled pesticides. Pesticide labels contain critical safety information that help prevent harm to human health and the environment.

In total, from December 2015 through December 2016, 17 companies paid $202,998 in civil penalties for federal Clean Air Act violations:

  • Yamagin Tsusho Company Limited: imported six mini-trucks from Japan. The mini-trucks did not have the proper certificates for their evaporative emissions components, such as fuel tanks and fuel hoses, and lacked the proper certificates for their catalytic converters. The company was required to ship the mini-trucks out of the United States and pay a $65,000 penalty. 
  • Pacific Rim International West Inc.: imported 104 all-terrain vehicles (ATVs) from China that contained catalysts not matching their description in the import application. The company was required to ship the ATVs out of the United States and pay a $30,000 penalty.
  • Vitacci Motorcycles Inc: imported 457 ATVs from China. The ATVs contained catalysts not matching their description in the import application. The company was required to ship the ATV’s out of the United States and pay an $18,000 penalty.
  • Ming’s International Inc.: imported 1,105 2-stroke spark ignition engines from China without the proper certification requirements. The company was required to ship the engines out of the United States and pay a $13,898 penalty.
  • Xcalibur Inc: imported 148 motorcycles from Taiwan. The motorcycles contained catalysts not matching their description in the import application. The company was required to ship the motorcycles out of the United States and pay a $13,300 penalty.
  • De Well Logistics, LLC: imported 1,060 uncertified chainsaw, mower, and outboard engines from China without the proper labels or certificates. The company was required to ship the engines out of the United States and pay a $10,100 penalty.
  • JMC Motors LLC: imported 12 ATVs from China without the proper certification requirements and containing catalysts not matching their description in the import application. The company was required to ship the ATVs out of the United States and pay an $8,800 penalty.
  • Value Group (SSR Motorsports): imported 108 scooters from China, that contained catalysts not matching their description in the import application. The company was required to ship the scooters out of the United States and pay an $8,400 penalty. 
  • Lil Pick Up, Inc.: imported 1,051 ATVs in 13 separate shipments from China, that lacked the proper certification requirements. The company was required to ship the ATVs out of the United States and pay a $7,000 penalty. 
  • Spira4U Co. Ltd.: imported 10 motorcycles from China. The motorcycles contained catalysts not matching their description in the import application. The company was required to ship the motorcycles out of the United States and pay a $6,500 penalty.
  • Stark International Inc.: imported 500 generators from China, that contained catalysts not matching their description in the import application. The company was required to ship the generators out of the United States and pay a $5,000 penalty.
  • CMT USA Industrial, Inc.: imported 252 types of construction equipment with uncertified nonadjustable carburetors or fuel tanks, in numerous shipments from China. The company was required to ship the equipment out of the United States and pay a $4,400 penalty. 
  • Innovative Energy Solutions Corporation: imported 78 gasoline generators from China without the proper certificates for evaporative emissions components such as fuel tanks and fuel hoses. The company was required to ship the generators out of the United States and pay a $4,200 penalty. 
  • Scooter Importer LLC: imported 48 scooters from China, that contained catalysts not matching their description in the import application. The company was required to ship the scooters out of the United States and pay a $2,700 penalty. 
  • Ridgerock Tools, Inc.: imported 100 generators from China, that contained catalysts not matching their description in the import application. The company was required to ship the generators out of the United States and pay a $2,100 penalty.
  • Rajysan, Inc.: imported 50 generators from China, that contained catalysts not matching their description in the import application. The company was required to ship the generators out of the United States and pay a $2,000 penalty.
  • Teng Chang Inc.: imported 20 marine engines from China, that contained spark-ignitions without proper labels or valid certificates. The company was required to ship the engines out of the United States and pay a $1,600 penalty.

EPA and CBP also prevented 15 shipments of pesticides from entering the country and brought a Federal Insecticide, Fungicide, and Rodenticide Act enforcement action against:

  • Dow AgroSciences LLC: imported 216 bags of the pesticide Glyphosate Technical FH from China. The pesticide, used to kill weeds, was produced in a facility in China, not in a U.S. facility as described by the company. The company fixed the paperwork violations and paid a $15,000 civil penalty.  

The Clean Air Act prohibits the importation or sale of any new engines or vehicles unless they are certified by EPA to meet federal emission standards. An EPA-issued certificate of conformity must cover every vehicle and engine sold in the U.S. To obtain a certificate of conformity, manufacturers or importers must submit an application to EPA that describes the engine or vehicle, including its emission control system. The application must also provide emissions data demonstrating that the engines and vehicles will meet applicable federal emission standards. For more information about importing vehicles and engines into the United States, please visit: www.epa.gov/importing-vehicles-and-engines

The Federal Insecticide, Fungicide, and Rodenticide Act requires that registered pesticides imported into the U.S. must be produced in an EPA-registered establishment and the product labels must bear an EPA registration number. Consumers should follow pesticide label directions and should look for the EPA registration number printed on product labels. For more information on importing and exporting pesticides and devices, please visit: www.epa.gov/compliance/importing-and-exporting-pesticides-and-devices

CBP is the unified agency within the Department of Homeland Security charged with the management, control and protection of our nation’s borders at and between the official ports of entry. It has regulatory authority for merchandise importation, re-export, seizure and forfeiture of unlawful products entering the country. For more information about how CBP secures the United States at our nation’s ports of entry, please visit: http://www.cbp.gov/border-security/ports-entry 

###

SenesTech to Ring Nasdaq Stock Market Closing Bell on January 20th

FLAGSTAFF, Ariz. and NEW YORK, Jan. 19, 2017 /PRNewswire/ — SenesTech, Inc. (NASDAQ: SNES), a developer of proprietary technologies for managing animal pest populations through fertility control, will celebrate its 2016 initial public offering („IPO”) by ringing the Nasdaq Stock Market closing bell in New York City on Friday, January 20th. The company began trading on the Nasdaq on December 8, 2016.

SenesTech co-founders Dr. Loretta Mayer and Dr. Cheryl Dyer will be joined by several members of the SenesTech team as they ring the closing bell at 4:00pm ET (2:00pm AZ time). Commencing around 3:45pm ET, a live stream of the Nasdaq Closing Bell will be available at: 
https://new.livestream.com/nasdaq/live
or http://www.nasdaq.com/about/marketsitetowervideo.asx.

„The listing of our shares on the Nasdaq was a tremendous milestone for SenesTech’s employees and early investors, and we are honored to ring the Nasdaq closing bell in celebration of this achievement,” said Dr. Loretta P. Mayer, Chair, CEO and co-founder of SenesTech.

Dr. Mayer continued, „SenesTech’s revolutionary technology for animal pest control changes the age-old kill and kill again practice by using cutting-edge science to get to the root cause of the problem: reproduction. Our solution aims to improve the quality of human life by reducing the chances of poisoned children and pets, reducing the spread of disease, getting more of the food we grow to our tables, and reducing infrastructure damage by rats.  We aim to do this by addressing the pest population in a more humane, sustainable, non lethal, effective and environmentally neutral, manner. We look forward to the opportunity of furthering our mission in the years to come.”

About SenesTech

SenesTech has developed an innovative technology for managing animal pest populations through fertility control as opposed to a lethal approach.

The Company’s first fertility control product, ContraPest®, will be marketed for use initially in controlling rat infestations. ContraPest’s novel technology and approach targets the reproductive capabilities of both sexes, inducing egg loss in female rodents and impairing sperm development in males. Using proprietary bait stations, ContraPest is dispensed in a highly palatable liquid formulation that promotes sustained consumption by rodent communities. ContraPest is designed, formulated and dispensed to be safe for handlers and non-target species such as wildlife, livestock and pets, in a biodegradable product. In contrast, the historical approach to managing rodent pest populations, rodenticides, carries a high risk of environmental contamination and the poisoning of non-target animals, pets and children.

We believe our non-lethal approach, targeting reproduction, is more humane, less harmful to the environment, and more effective in providing a sustainable solution to pest infestations than traditional lethal pest management methods. There is currently no other non-lethal fertility control product approved by the Food and Drug Administration (FDA), or the Environmental Protection Agency (EPA), for the management of rodent populations.  We believe ContraPest® will establish a new paradigm in rodent control, resulting in improved performance in rodent control over rodenticides, without the negative environmental effects of rodenticides.  For more information visit the SenesTech website at www.senestech.com.

Safe Harbor Statement  
This release contains „forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended and such forward-looking statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. „Forward-looking statements” describe future expectations, plans, results, or strategies and are generally preceded by words such as „may,” „future,” „plan” or „planned,” „will” or „should,” „expected,” „anticipates,” „draft,” „eventually” or „projected.” You are cautioned that such statements are subject to a multitude of risks and uncertainties that could cause future circumstances, events, or results to differ materially from those projected in the forward-looking statements, including the risks that actual results may differ materially from those projected in the forward-looking statements as a result of various factors and other risks identified in our filings with the Securities and Exchange Commission. All forward-looking statements contained in this press release speak only as of the date on which they were made and are based on management’s assumptions and estimates as of such date. We do not undertake any obligation to publicly update any forward-looking statements, whether as a result of the receipt of new information, the occurrence of future events or otherwise.

 

SOURCE SenesTech, Inc.

To Build Or Not To Build Parking: Automated Parking Lifts Have Changed The Rules

OAKLAND, Calif., Jan. 19, 2017 /PRNewswire/ — CityLift CEO, Scott Gable recently sat a on a speaker’s panel at a conference called the „Future of Mixed Use Real Estate Development”. As these panels typically go, it only took about 2 minutes before the conversation veered into parking.

One developer spoke up that they were truly stuck on what to do in their new mixed use project.  Their city planning department was willing to relax parking requirements completely. However, their tenants would need parking today, and if they didn’t provide enough parking the local community would actively resist the project, fearing the new influx of cars on their already cramped streets.  

The developer was also worried in 10-15 years their development may not need as much parking if more people use ride sharing or alternative forms of transportation.  

Should they make the investment to meet today’s demand?

Should they under build today’s demand even if it means losing some prospective tenants?  

Would community resistance kill their project if they don’t build enough parking?

Up to now parking has been a zero-sum game because of how conventional garages are designed and constructed. An average garage requires three to six times more square feet than the actual dimension of a car to accommodate drive aisles, ramps and standard parking space dimensions.  Conventional garages are increasingly expensive to build.

What if the developer doesn’t need the amount of parking in the future?

Would they be stuck with a concrete structure with low ceilings and ramps and no other purpose?

The way out of this dilemma is to USE AUTOMATED PARKING LIFTS today. Automated parking lifts are not a new concept, but up until now much of the development has occurred in Europe and Asia. In Japan alone there are over 1.6 million automated parking spaces in one form or another.

Based in Oakland, CA, CityLift Parking is building some of the most innovative, easy-to-use, and affordable automated technologies in the United States. CityLift reduces the square footage needed per car up to 80% by using vertical space more efficiently, eliminating ramps, concrete slabs and in some cases eliminating drive aisles altogether.  

This means a developer can meet today’s parking need with much less space, freeing up land for other uses.

Construction expenses also go down. For example, three car levels in an automated structure uses the same vertical space as a 2-level conventional garage. Construction hard costs are saved by eliminating an entire floor of concrete, an elevator stop, and ramps.

As for going below ground, the space savings per car can eliminate some or all of the need to go subterranean. The all-in cost of a fully subterranean garage can often be cut in half or more by using automated parking. 

In addition, since parking lifts are equipment they can be depreciated over 7 years instead of the 29 years for a physical building, helping to improve the after tax returns in the early years of the project.

The best part is the space for automated parking lifts can be repurposed if parking demand goes down in 10-15 years. When the parking is no longer needed you disassemble the structure, move it out, and regain square footage for amenities or possibly even more rentable space. It’s like getting a free option for the future without making a sacrifice on meeting today’s needs.

Solving parking today doesn’t need to be a dilemma. Automated parking lifts are an intelligent solution that’s ready to meet your needs, both today and in the future- whatever that may hold.

 

SOURCE CityLift Parking

Maddie’s Fund Invests $2 Million in Adopt-a-Pet.com

PLEASANTON, CA–(Marketwired – January 19, 2017) – Maddie’s Fund®, a national family foundation established by Dave and Cheryl Duffield to revolutionize the status and well-being of companion animals, has made a $2 Million investment in Adopt-a-Pet.com to help expand its technology and bolster public interest and involvement in pet adoption and fostering.

Adopt-a-Pet.com is North America’s largest nonprofit pet adoption website and is the search engine platform for the Shelter Pet Project, a national advertising campaign dedicated to making shelter pet adoption a national conversation. This investment will allow Adopt-a-Pet.com to make advancements to its current technology that include optimizations in searching for a specific type of pet, and provide real-time updates to ensure pet availability. It will also offer actionable data to better understand all types of adopters and volunteers, and help improve customer service for both adopters and shelter organizations.

“Technology has revolutionized the way we connect adopters, volunteers and foster care givers with shelter and rescue organizations. Adopt-a-Pet.com is a leader in making connections happen, and this investment will grow their capabilities faster,” said Lars Rabbe, Chief Information Officer at Maddie’s Fund. “Most importantly, the advancements will help to find all the dogs and cats of America loving homes, and help make adoption the first choice when choosing a pet.”

“Thanks to Maddie, this investment will allow us to innovate in ways that until this time were just not possible,” said David Meyer, co-founder and CEO of Adopt-a-Pet.com. “We are honored to play a significant role in elevating shelter pets’ visibility and helping people find their match.”

About Maddie’s Fund

Maddie’s Fund® is a family foundation created in 1994 by Workday co-founder Dave Duffield and his wife, Cheryl, who have endowed the Foundation with more than $300 million. Since then, the Foundation has awarded more than $187.8 million in grants toward increased community lifesaving, shelter medicine education, and pet adoptions across the U.S. The Duffields named Maddie’s Fund after their Miniature Schnauzer Maddie, who always made them laugh and gave them great joy. Maddie was with Dave and Cheryl from 1987 – 1997 and continues to inspire them today.

Maddie’s Fund is the fulfillment of a promise to an inspirational dog, investing its resources to create a no-kill nation where every dog and cat is guaranteed a healthy home or habitat. #ThanksToMaddie.

Maddie’s Fund Invests $2 Million in Adopt-a-Pet.com

PLEASANTON, CA–(Marketwired – January 19, 2017) – Maddie’s Fund®, a national family foundation established by Dave and Cheryl Duffield to revolutionize the status and well-being of companion animals, has made a $2 Million investment in Adopt-a-Pet.com to help expand its technology and bolster public interest and involvement in pet adoption and fostering.

Adopt-a-Pet.com is North America’s largest nonprofit pet adoption website and is the search engine platform for the Shelter Pet Project, a national advertising campaign dedicated to making shelter pet adoption a national conversation. This investment will allow Adopt-a-Pet.com to make advancements to its current technology that include optimizations in searching for a specific type of pet, and provide real-time updates to ensure pet availability. It will also offer actionable data to better understand all types of adopters and volunteers, and help improve customer service for both adopters and shelter organizations.

“Technology has revolutionized the way we connect adopters, volunteers and foster care givers with shelter and rescue organizations. Adopt-a-Pet.com is a leader in making connections happen, and this investment will grow their capabilities faster,” said Lars Rabbe, Chief Information Officer at Maddie’s Fund. “Most importantly, the advancements will help to find all the dogs and cats of America loving homes, and help make adoption the first choice when choosing a pet.”

“Thanks to Maddie, this investment will allow us to innovate in ways that until this time were just not possible,” said David Meyer, co-founder and CEO of Adopt-a-Pet.com. “We are honored to play a significant role in elevating shelter pets’ visibility and helping people find their match.”

About Maddie’s Fund

Maddie’s Fund® is a family foundation created in 1994 by Workday co-founder Dave Duffield and his wife, Cheryl, who have endowed the Foundation with more than $300 million. Since then, the Foundation has awarded more than $187.8 million in grants toward increased community lifesaving, shelter medicine education, and pet adoptions across the U.S. The Duffields named Maddie’s Fund after their Miniature Schnauzer Maddie, who always made them laugh and gave them great joy. Maddie was with Dave and Cheryl from 1987 – 1997 and continues to inspire them today.

Maddie’s Fund is the fulfillment of a promise to an inspirational dog, investing its resources to create a no-kill nation where every dog and cat is guaranteed a healthy home or habitat. #ThanksToMaddie.